The GeoMx® Immune Pathways Panel is designed to profile key aspects of tumor biology, the tumor microenvironment, and the immune response, with spatial resolution from distinct regions of interest with a single tissue section.
This panel allows you to profile the expression of 84 RNA targets covering several pathways. You will be able to:
- Profile the global immune response
- Assess microenvironment immune activity
- Quantify tumor reactivity
- Measure the 18-gene Tumor Inflammation Signature (TIS) known to be associated with response to PD-1/PD-L1 inhibitor pathway blockade
Furthermore, it can be customized with up to 10 additional targets of interest.
The GeoMx® Immune Pathways Panel is compatible with RNAscope® technology and antibody morphology markers for tissue imaging and ROIs selection.
The read out is performed by nCounter, and the software GeoMx DSP data center provides an end-to-end software solution from image acquisition and region of interest selection to a fully integrated data analysis experience.
For more information about the pathways and processes included in the panel, please, consult the product file you can download below or visit the NanoString web:
