Human leukocyte antigens (HLA) are a highly polymorphic system of glycoproteins that have a functional role in the presentation of peptides to the immune system. HLA molecules can become the targets of antibody responses in people during pregnancy, transfusion or organ transplant rejection. The presence or absence of these HLA-specific antibodies has a role in determining the survival of transplant allografts.
LIFECODES LSA kits are designed to detect IgG antibodies to HLA Class I or II glycoproteins. They are composed of different Luminex beads to which purified recombinant Class I or II HLA glycoproteins are conjugated. Each bead has a different HLA protein.
