Molecular Genetics

Comprehensive spatial study of cellular biology, with full coverage of protein coding genes, and application in several fields: oncology, immunology, neuroscience, developmental biology...

Twist Human Core Exome and Twist Human Core Exome + Ref Seq are the two capture solutions for human exome sequencing by Twist Bioscience. The superior performance of the Twist Core Exome provides the optimal solution for sequencing human coding genes, while focusing on the most accurate curated subset of genes: that of the CCDS…

Detection of 6 mutations associated with dihydropyrimidine dehydrogenase deficiency.

Analyses the 4 most relevant mutations associated with increased risk of thrombosis

Global genetic diagnostic test and risk stratification of patients with clinical suspicion of familial hypercholesterolaemia.

Molecular diagnosis of Male Factor Infertility (aneuploidy, microdeletions, CBAVD)

Expression study of genes related to Alzheimer’s Disease.

Study of the relationship between autoimmune disease associated germline variants and gene expression.

Study of relevant genes in autoimmune disease, chronic inflammatory disease and immunotherapy-related adverse events (human panel and mouse panel).

Study of gene expression aimed at the development of CAR-T cell therapies.

Study of the genes which participate in the fibrotic process.

Comprehensive expression study of genes in astrocytes, microglia, and oligodendrocytes, allowing a better understanding of neurodegenerative and neuroinflammatory disorders and neurotrauma.

Global study of the individual’s immune response (human or mouse) to infection.

Study of the individual’s immune response to transplanted tissue.

Gene expression study of genes related to T cell, B cell, and NK cell exhaustion in diverse contexts, including cancer and infectious disease.

Expression study of genes related to immunology.

Study of the early inflammatory response.

Study of genes involved in core metabolic processes and immunometabolism.

Comprehensive gene expression study of myeloid-derived cells.

Comprehensive expression study of genes from pathways, processes and cell types involved in neuroinflammation.

Expression study of genes involved in six fundamental themes of neurodegeneration: neurotransmission, neuron-glia interaction, neuroplasticity, cell structure integrity, neuroinflammation, and metabolism.

Comprehensive study of the immune response, optimized for immuno-oncology research, including essential genes for the tumor biology and the tumoral microenvironment.

Comprehensive study of genes involved in the tumoral immune evasion and the response to immunotherapy, including essential genes for the tumoral microenvironment and the immune response.

Comprehensive study of genes involved in major cancer pathways, including essential genes for the tumor biology, the tumoral microenvironment and the immune response.

Comprehensive study of genes involved in processes and mechanisms related to cancer progression, including essential genes for tumor biology, the tumoral microenvironment and the immune response.

Study of gene expression aimed at the development of Stem Cell therapies.

Comprehensive study of dysfunctional cell signaling in cancer, including essential genes for the tumor biology, the tumoral microenvironment and the immune response.

Non-invasive preimplantation chromosome screening technique.

Automatic extractor of genetic material

PGT-A (Preimplantation Genetic Testing for Aneuploidies) solution, that combines WGA and library preparation for NGS (MALBAC® technology).