The GeoMx® Whole Transcriptome Atlas (WTA) panel is designed to perform a complete spatial transcriptomic study in human or mouse, selecting regions of interest in the tissue (fresh, frozen or fixed) and obtaining an accurate expression profile without damaging the tissue or microdissecting it.
This panel allows you to profile the expression of over 18,00 genes, making possible full coverage of protein coding genes.
- Spatial Profiling: Possibility to explore gene expression in regions of interest, being able to identify the cellular content and metabolic pathways involved.
- Biomarker Discovery: Localization and expression of therapeutic targets “in situ” to identify processes and treatment response.
- Pathway Analysis: The annotated content provides insight into the activation status of signaling pathways within the tissue compartments of interest.
The GeoMx® WTA is compatible with RNAscope® technology and antibody morphology markers for tissue imaging and ROIs selection.
The read out is performed by Next-Generation Sequencing (NGS) with Illumina platforms, and the software GeoMx DSP data center provides an end-to-end software solution from image acquisition and region of interest selection to a fully integrated data analysis experience.
For more information about this panel, please, consult the product file you can download below.