The PanCancer Immuno-Oncology 360 Panel is designed for a comprehensive study (360° view) of the impact of immune evasion in the tumor microenvironment, and the identification of potentially prognostic, predictive or mechanism of action signatures for immunotherapy. Furthermore, it includes genes related to the tumor biology, the tumoral microenvironment and the immune response.
It incorporates 48 potentially predictive Research Use Only (RUO) biological signatures including the 18-gene Tumor Inflammation Signature (TIS), which measures a peripherally suppressed, adaptive immune response and has been shown to correlate with response to checkpoint inhibitors.
It includes 770 genes (request list) involved in 13 key pathways and processes in the tumor biology, microenvironment and immune response.
For more information about the biological signatures, and the pathways and processes included in the panel, please, consult the product file you can download below or visit the NanoString web:
Panel Customization
The PanCancerIO 360 Panel could be combined with a Panel Plus, which will allow you to add up to 55 genes chosen by the client.
If you want to check that this panel is the most suitable for you, you can go to the NanoString Panel Pro panel selection tool:
