October 22, 18:00 h | Online
In this webinar, hear Teresa Cardoso Delgado, PhD, from CIC bioGUNE in Spain discuss hepatic transcriptional profiling of dietary mouse models of non-alcoholic fatty liver disease (NAFLD) using the nCounter® Metabolic Pathways Panel.
Pathways involved in fatty acid metabolism and mitochondrial respiration decreased as the model of NAFLD progressed, along with pathways responsible for amino acid synthesis and arginine metabolism.
In addition, immune cell profiling using cell typing signatures embedded in the Metabolic Pathways Panel revealed an enrichment of neutrophils, macrophages, dendritic cells, and CD45 cells in the most harmful dietary models, and these findings correlated with IHC.
Speakers:
Plenary: Teresa Cardoso Delgado, PhD
Liver Disease Lab, CIC bioGUNE