SCOPE™ Kits
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PGTA-ChromInst® (Preimplantation Genetic Testing for Aneuploidies) is a PGT-A solution. It combines in a single step WGA (Whole Genome Amplification) and library preparation for NGS (Next Generation Sequencing), (MALBAC® technology), guaranteeing a uniform and efficient amplification of DNA (MALBAC® technology).
MALBAC® technology
WGA methods are prone to introduce amplification bias, as they amplify some regions better than others. However, MALBAC® (Multiple Annealing and Looping Based Amplification Cycles) technology results in amplification products that have complementary ends capable of forming loops of DNA, which enhances the quasi-linearity of amplification. In this way, much better amplification uniformity is achieved than with the other WGA methods described to date.
High genome coverage and amplification of >90% of loci is achieved with this technology. In addition, the ADO (Allele Drop Out) rate is <10%.
Features:
ChromGO™
Simple data analysis solution, which allows you to quickly customize your data analysis reports on both online and local servers.
Features:
Who is it for?
Product name | Nº | Size |
---|---|---|
PGTA-ChromInst® | YK-PGT-A-48 | 48 reactions |
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