Free DNA Fetal Kit® RhD

The determination of fetal RHD genotyping in maternal blood allows:

• Establish if a negative RhD pregnant woman requires the immunoprophylaxis vaccine administration.
• The management of a risky pregnancy, in RhD negative pregnants with anti-D, to determine if the fetus is at risk of Haemolytic Disease of the fetus and Newborn (EHRN).
• Avoid the unnecessary administration of anti-D immunoglobulin, in case of negative fetal RhD genotype, thus avoiding its associated risk.
• Increase the availability of anti-D immunoglobulin for use after potential sensitization events (PSE) in pregnancies where the result of Non-invasive Prenatal Diagnosis (NIPD) for the fetal RhD genotype is positive.
• Avoid unnecessary painful injections for women in whom Non-Invasive Prenatal Diagnosis for the fetal RhD genotype is negative.
• Reduce the number of prenatal appointments for prophylactic anti-D treatment and the amount of anti-D immunoglobulin used.
• Reduce the anxiety associated with potential sensitization events for RhD negative women when the outcome of NIPD for the fetal RhD genotype is negative.
• Provide information to allow RhD negative women to make an informed decision about whether or not they should receive anti-D immunoglobulin treatment based on the outcome of the fetal genotype.

The Free Fetal DNA kit is a non-invasive test for fetal Rh detection from maternal plasma samples by Real Time PCR (RT-PCR).

The sample is taken after 11 weeks of gestation.