The GeoMx® Whole Transcriptome Atlas (WTA) is designed for comprehensive profiling of cellular biology, with spatial resolution from distinct regions of interest with a single tissue section. It can be used for research in several fields: oncology, immunology, neuroscience, developmental biology...
This panel allows you to profile the expression of over 18,00 genes, making possible full coverage of protein coding genes.
- Spatial Profiling: Possibility of identifying the expression of genes in specific regions of the tissue, with mapping of specific pathways and functions, as well as the abundance of cell types.
- Biomarker Discovery: Identification of biomarkers associated with a localization in the tissue, with the potential to identify processes or therapeutic targets not located with other types of assays on the complete tissue.
- Pathway Analysis: The annotated content provides a spatial mapping of the activation of signaling pathways within discrete compartments of the tissue.
The GeoMx® WTA is compatible with RNAscope® technology and antibody morphology markers for tissue imaging and ROIs selection.
The read out is performed by Next-Generation Sequencing (NGS), and the software GeoMx DSP data center provides an end-to-end software solution from image acquisition and region of interest selection to a fully integrated data analysis experience.
For more information about this panel, please, consult the product file you can download below.
|Product||Product Description||Quantity||Catalog Number|
|GeoMx Human Whole Transcriptome Atlas Human RNA for Illumina Systems||RNA probe set that targets 18,000+ transcripts for human protein coding genes plus ERCC negative controls to profile the whole trasncriptome. Excludes uninformative high expressing targets such as ribosomal subunits. Includes RNA probes designed for Illumina NGS readout with the Seq Code library prep||4 slides||GMX-RNA-NGS-HuWTA-4|
|GeoMx Mouse Whole Transcriptome Atlas Mouse RNA for Illumina Systems||RNA probe set that targets 21,000+ transcripts for mouse protein coding genes plus ERCC negative controls to profile the whole trasncriptome. Excludes uninformative high expressing targets such as ribosomal subunits. Includes RNA probes designed for Illumina NGS readout with the Seq Code library prep||4 slides||GMX-RNA-NGS-MsWTA-4|
|GeoMx Solid Tumor TME Morphology Kit Human RNA Compatible||Morphology kit for visualization of human solid tumors and the tumor microenvironment. For use with RNA assays. Includes fluorescent antibodies against Pan-CK, CD45, and a nuclear stain||12 slides||GMX-RNA-MORPH-HST-12|
|GeoMx Melanoma TME Morphology Kit Human RNA Compatible||Morphology kit for visualization of human melanoma and the tumor microenvironment. For use with RNA assays. Includes fluorescent antibodies against S100B/Pmel17, CD45, and a nuclear stain||12 slides||GMX-RNA-MORPH-HMEL-12|
|GeoMx Seq Code Pack Compatible with Illumina Systems||NGS readout reagents for GeoMx DSP RNA and protein analysis. Includes two Seq Code primer plates (choice of A&B, C&D, E&F, o G&H) and two universal enzyme master mixes||192 areas of interest (AOI)||GMX-NGS-SEQ-[XX]|
|GeoMx RNA Slide Prep Kit for FFPE||Sample prep reagents for GeoMx DSP RNA analysis. Includes Buffer W, Buffer S, and Buffer R||12 slides||GMX-PREP-RNA-FFPE-12|
|GeoMx DSP Collection Plate||Barcoded collection plates for use in the GeoMx DSP. Required for AOI tracking. Kit includes 12 plates covering 1,152 AOI||1 pack||GMX-DSP-COLL-PLT|
|GeoMx DSP Instrument Buffer Kit||Buffer kit for the GeoMx DSP. Includes Buffer S and Buffer H. Sufficient for -48 samples with -18 AOI each. Volume requirements may vary based on experimental design||1 kit||GMX-DSP-BUFF-KIT|