Human Platelet Antigens (HPA) Ready Gene typing

Human Platelet Antigens (HPA) are glycoproteins expressed on the membrane of platelets. Antibodies against the Human Platelet Antigens can cause immune reactions in the recipient´s bood leading to the lysis of the transfused platelets.

HPA-Ready Gene enables the detection of the alleles HPA-1a/b, HPA-2a/b, HPA-3a/b, HPA-4a/b, HPA-5a/b and HPA-15a/b.

In addition to this kit, There are two other options to increase the number of detected alleles.

• HPA ReadyGene plus: extension of the standard (HPA 6a/b y HPA 9a/b) 

HPA 1a/b ReadyGene: screening up to 96 samples for the HPA-1 polymorphism. Genotyping of the mother with regard to HPA-1 makes it possible to predict possible neonatal alloimmune thrombocytopenia