CatalogImmunology and transplantationImmune response and biomarkers
The Autoimmune Profiling Panel is designed for the study of gene expression related to autoimmune disease, chronic inflammatory disease and immunotherapy-induced adverse events (human panel and mouse panel). Some of the covered diseases are Rheumatoid Arthritis, Type 1 Diabetes, Multiple Sclerosis or Psoriasis.
It includes 770 genes (downloadable list) involved in 35 pathways and processes related to the already said pathologies and allows you to measure the relative abundance of 14 different immune cell types.
For more information about the pathways included in the panel, immune cell profiling, disease coverage, targets for approved and investigational therapies and so on, please consult the product file you can download below.
Some application examples for this panel are therapeutic mechanism of action (MOA) studies, immunotherapy-induced adverse event investigations, discovery/validation of disease and therapeutic specific biomarkers, development of predictive signatures of drug response…
Panel customization
The Autoimmune Profiling Panel could be combined with a Panel Plus, which will allow you to add up to 55 genes chosen by the client.
If you want to check that this panel is the most suitable for you, you can go to the NanoString Panel Pro panel selection tool:
| Product | Product Description | Quantity | Catalog Number |
|---|---|---|---|
| nCounter Human Autoimmune Profiling Panel | Includes 770 genes; 20 internal reference genes for data normalization | 12 Reactions | XT-CSO-HAIP1-12 |
| nCounter Mouse Autoimmune Profiling Panel | Includes 770 genes; 20 internal reference genes for data normalization | 12 Reactions | XT-CSO-MAIPI1-12 |
| nCounter Master Kit (Max or FLEX Systems) Reagents and Cartridges | Reagents, cartridges, and consumables necessary for sample processing on nCounter MAX and FLEX Systems | 12 Reactions | NAA-AKIT-012 |
| nCounter SPRINT Cartridge 1 Cartridge, 12 lanes | Sample Cartridge for nCounter SPRINT System | 12 Reactions | SPRINT-CAR-1.0 |
| nCounter SPRINT Reagent Pack | nCounter SPRINT Reagent Pack containing Reagents A, B, C, and Hybridization Buffer | 192 Reactions | SPRINT-REAG-KIT |
| nCounter Human Autoimmune Profiling Panel Primer Pools | MTE primer pools for Low Input RNA profiling (770 genes) 750 autoimmune disease related human genes + 20 internal reference controls. Master Kit, RNA Low Input Kit, and Panel CodeSet Required | 12 Reactions | PP-HAIP1-12 |
| nCounter Mouse Autoimmune Profiling Panel Primer Pools | MTE primer pools for Low Input RNA profiling (770 genes) 750 autoimmune disease related mouse genes + 20 internal reference controls. Master Kit, RNA Low Input Kit, and Panel CodeSet Required | 12 Reactions | PP-MAIP1-12 |
