CatalogOncologySolid Tumor
The Tumor Signaling 360 Panel is designed for a comprehensive study (360° view) of dysfunctional cell signaling in cancer, allowing a better understanding of the interactions of tumor cells with the tissue milieu. Furthermore, it includes genes related to the tumor biology, the tumoral microenvironment and the immune response. This panel could help you with the development of tumoral signaling-targeted therapies.
It incorporates the 18-gene Tumor Inflammation Signature (TIS), which measures a peripherally suppressed, adaptive immune response and has been shown to correlate with response to checkpoint inhibitors.
It includes 780 genes (request list) involved in more than 40 key pathways and processes in the tumor biology, microenvironment and immune response, for example, genes related to tumorigenesis, metastasis, and inflammation.
For more information about the pathways and processes included in the panel, the TIS, or the possibility of measuring the relative abundance of 14 different immune cell types, please, consult the product file you can download below or visit the NanoString web:
Panel Customization
The Tumor Signaling 360 Panel could be combined with a Panel Plus, which will allow you to add up to 55 genes chosen by the client.
If you want to check that this panel is the most suitable for you, you can go to the NanoString Panel Pro panel selection tool:
| Product | Product Description | Quantity | Catalog Number |
|---|---|---|---|
| nCounter Human Tumor Signaling 360 Panel + Panel Standard | Includes 780 genes; 20 internal reference genes for data normalization. The Tumor Signaling 360 panel includes a Panel Standard containing a pool of synthetic DNA oligonucleotides that correspond to the target sequence of each of the 780 unique probe targets in the panel. This allows for normalization for possible user, instrument, and lot-to-lot variation. | 12 Reactions | XT-CSO-H-TS360-12 |
| nCounter Mouse Tumor Signaling 360 Panel + Panel Standard | Includes 780 genes; 20 internal reference genes for data normalization. The Tumor Signaling 360 panel includes a Panel Standard containing a pool of synthetic DNA oligonucleotides that correspond to the target sequence of each of the 780 unique probe targets in the panel. This allows for normalization for possible user, instrument, and lot-to-lot variation. | 12 Reactions | XT-CSO-M-TS360-12 |
| nCounter Master Kit (Max or FLEX Systems) Reagents and Cartridges | Reagents, cartridges, and consumables necessary for sample processing on nCounter MAX and FLEX Systems | 12 Reactions | NAA-AKIT-012 |
| nCounter SPRINT Cartridge 1 Cartridge, 12 lanes | Sample Cartridge for nCounter SPRINT System | 12 Reactions | SPRINT-CAR-1.0 |
| nCounter SPRINT Reagent Pack | nCounter SPRINT Reagent Pack containing Reagents A, B, C, and Hybridization Buffer | 192 Reactions | SPRINT-REAG-KIT |
